Using the SIR Model to Analyze the Epidemiological Situation in Kazakhstan and Neighboring Countries

In this paper, we study the epidemic situation in Kazakhstan and neighboring countries, taking into account territorial features in emergency situations. As you know, the excessive concentration of the population in large cities and the transition to a world without borders created ideal conditions for a global pandemic. The article also provides the results of a detailed analysis of the solution approaches to modeling the development of epidemics by types of models (basic SIR model, modified SEIR models) and the practical application of the SIR model using an example (Kazakhstan, Russia, Kyrgyzstan, Uzbekistan and other neighboring countries). The obtained processing results are based on statistical data from open sources on the development of the COVID-19 epidemic. The result obtained is a general solution of the SIR-model of the spread of the epidemic according to the fourth-order Runge-Kutta method. The parameters β, γ, which are indicators of infection, recovery, respectively, were calculated using data at the initial phase of the Covid 2019 epidemic. An analysis of anti-epidemic measures in neighboring countries is given. © 2022 Copyright for this paper by its authors. Use permitted under Creative Commons License Attribution 4.0 International (CC BY 4.0).

From Landlocked to Land-Linked: Kazakhstan as a Transport and Logistics Centre Within the Silk Road Economic Belt

Kazakhstan, being in the centre of the Eurasian continent, is a landlocked country that shares a border both with China and Russia. Since its independence in 1991, Kazakhstan has attempted to take advantage of its geographical location, by becoming a bridge between Europe and China. To achieve this goal, Kazakhstan has actively participated in the construction of the Silk Road Economic Belt (SREB) and joined the Asian Infrastructure Investment Bank (AIIB) as one of the founding countries. These activities have brought Kazakhstan not only the opportunity to become a transport and logistics hub but also to reduce its dependence on Russian infrastructure. In the light of the current war in Ukraine, the transportation of goods through the territory of Kazakhstan becomes more crucial to China as it can bypass Russia. Though the SREB has enabled Kazakhstan to export more resources and become more independent from Russian infrastructure, same time, China might become a threat to Kazakhstan's economic independence, as it will be more connected to the Chinese infrastructure. This chapter also shows that during the COVID-19 pandemic, China's economic policy in Kazakhstan is evolving. China now spends less on large infrastructure projects and focuses more on Kazakhstan's raw materials. This study aims to take a comprehensive look at Kazakhstan's relationship with China, as well as the implications of the SREB for Kazakhstan and its transport capacity. © The Editor(s) (if applicable) and The Author(s), under exclusive licence to Springer Nature Switzerland AG 2022.

A Review on Solar Energy Policy and Current Status: Top 5 Countries and Kazakhstan

The article describes the world's experience in developing the solar industry. It discusses the mechanisms of state support for developing renewable energy sources in the cases of five countries that are the most successful in this area—China, the United States, Japan, India, and Germany. Furthermore, it contains a brief review of state policy in producing electricity by renewable energy facilities in Kazakhstan. This paper uses statistical information from the International Renewable Energy Agency (IRENA), the International Energy Agency (IEA), British Petroleum (BP), and the Renewable Energy Network (REN21), and peer-reviewed sources. The research methodology includes analytical research and evaluation methods to examine the current state of solar energy policy, its motivators and incentives, as well as the prospects for its development in Kazakhstan and in the world. Research shows that solar energy has a huge development potential worldwide and is sure to take its place in gross electricity production. This paper focuses on the selected economic policies of the top five countries and Kazakhstan, in what may be considered a specific research limitation. Future research suggestions for the expansion of Renewable Energy (RE) in Kazakhstan could include analysing the impact of introducing dedicated policies and incentives for solar systems and exploring the benefits and challenges of implementing large RE zones with government–business collaboration.

Research in a Closed Political Context, COVID, and Across Languages: Methodological Lessons, Messages, and Ideas

This study offers a number of contemporary qualitative and mixed methods research lessons regarding cross-language research and research in closed social and political contexts such as post-Soviet countries, especially how such research may be adapted to disruptions like those posed by the COVID pandemic or other disasters. The lessons draw from a study of policy learning among government officials in Kazakhstan which illustrated several methodological strengths and weaknesses and generated a number of methodological recommendations. In particular, while the literature on best practices for research in closed contexts emphasizes deep interactions to develop trust, the COVID pandemic and other disruptions may force researchers to transition to online modalities and constrain options. We suggest strategies to overcome these limitations, including supplementing findings from interviews with content analysis or other multimethod approaches. Additionally, we argue that researchers in post-Soviet and post-colonial contexts must be particularly attuned to the challenges of cross-language research and the combination of local languages with the language of the colonial power. These lessons hold relevance for researchers working in a variety of contexts as they conduct research during times of disasters and geopolitical instability. [ FROM AUTHOR] Copyright of International Journal of Qualitative Methods is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)

Strategies for implementation of green roofs in developing countries

PurposeReportedly, green roof (GR) makes a significant contribution towards a truly sustainable-built environment;however, its implementation is yet to hit a sufficient level in developing countries. Thus, this study assesses GR implementation strategies in developing countries by providing a comparative analysis through experts in Kazakhstan, Malaysia and Turkey.Design/methodology/approachThe study adopts a four-step methodological approach to achieve the research aim: literature review, focus group discussion, fuzzy analytical hierarchy process (FAHP) analysis and correlation analyses. First, a literature review followed by a focus group discussion is used to determine 18 (out of 25 initially) strategies for the selected context and these are classified into three categories: governmental and institutional support, knowledge and information and policy and regulation. Afterward, the identified GR strategies are evaluated using the FAHP with the data gathered from the experts in the countries studied. Finally, correlation analyses were used to observe the strength of agreement between the assessments of experts from the included countries.FindingsThe findings indicate that financial incentives, low-cost government loans and subsidies and tax rebates are the essential strategies for the wider adoption of GR. Evaluating the policy and regulations strategies also showed that mandatory GR policies and regulations and better enforcement of the developed GR policies are ranked as the most prominent strategies. The findings show a low level of agreement among respondents from Kazakhstan, while there is a high level of agreement between the experts in Malaysia and Turkey.Research limitations/implicationsThe research contribution is twofold. First (research implication), the study identifies the strategies through a complete literature review. Second, the identified strategies are evaluated through the lenses of experts in three developing countries which are hoped to provide (practical contribution) a better understanding of the most effective strategies that require attention and enable the frontline stakeholders (particularly government authorities) to focus on them.Originality/valueThe study findings provide a good point of departure to explore the strategies for broader adoption of GRs in developing economic setting.

The influence of post-COVID syndrome on cognitive functions of students

A survey of senior students of the Faculty of General Medicine of the NAO MUK who had recovered from Covid-19 was conducted. The disease in all respondents proceeded in a mild form or moderate severity. Post-covid syndrome developed in students who had a coronavirus infection in the form of moderate severity. The most frequent complications were loss of smell and taste, cough and shortness of breath, as well as cognitive dysfunction in the form of impaired attention, memory and thinking. The decline in performance is associated with the above violations of the central nervous system.

The impact of COVID-19 on the indicators of the oncological service for breast cancer in Kazakhstan

Introduction. According to International Agency for Research on Cancer in 2040, about 3 million new cases of breast cancer (BC) are predicted and about 1 million women are expected to die from this pathology. The aim of the study to assess the impact of COVID-19 on the indicators of the oncological service for breast cancer in Kazakhstan. Material and research methods. The main method was a retrospective study using descriptive, analytical methods of biomedical statistics and data of the Ministry of Health of the Republic of Kazakhstan - form No.7 and 35 regarding BC (ICD 10 - C50) for 2011-2020. Results. For 2011-2020 42,376 new cases of BC and 12,914 deaths from this pathology were registered. The average annual crude incidence rate was 46.4+or-1.10/0000 (95%CI=44.3-48.5), and increased from 40.8+or-0.70/0000 (2011) to 51 .3+or-0.70/0000 in 2019 and then decrease to 44.2+or-0.70/0000 in 2020 (p<0.001). In dynamics, mortality rates tended to (p<0.001) decrease from 16.1+or-0.40/0000 (2009) to 11.9+or-0.40/0000 in 2019 and 11.5+or- 0.40/0000 in 2020, and the average annual crude mortality rate was 14.2+or-0.60/0000 (95%CI=13.1-15.3). Indicators of early diagnosis (stage I-II) improved from 73.4% (2011) to 86.9% in 2019, and decreased to 84.2% in 2020. Proportion of patients with stage III decreased (from 20.9% in 2011 to 8.4% in 2019 and to 10.0% in 2020) and stage IV (from 5.6% to 4.2% and 5.0%, respectively), i.e. neglect rates are declining. The indicators of morphological verification improved from 95.7% to 99.4% over the years. Conclusions. As a result of the analysis, an improvement in the indicators of morphological verification, early diagnosis, a decrease in the neglect and mortality rates were established. The trends in 2011-2019 differed significantly from the period from 2011-2020, which is due to the COVID-19 pandemic on the registration of BC.

Presenting, Representing, and Misrepresenting COVID-19 in the Five Central Asian States: The Political Underpinnings of Official State Coronavirus Websites in Authoritarian Regimes

In response to the COVID-19 pandemic, each of the five Central Asian states (Kazakhstan, Uzbekistan, Kyrgyzstan, Tajikistan, and Turkmenistan) took notably different approaches to presenting coronavirus-related information on the internet through official websites. To understand these differences, this chapter engages with literature that looks at how states use websites for self-promotion, what shapes the decision-making of those elites in control of a state, and who sanctions the creation of those websites. Pairing a quantitative presentation of these websites' qualities with an analysis of text and images, the differences among these coronavirus websites are sketched out before they are situated in the political circumstances of the states which designed them. This analysis finds that coronavirus websites developed by Central Asian states are not solely depoliticized platforms for disseminating information to the public, but, rather, are inexorably linked to the concerns and objectives of state elites;in turn these elite agendas are reflected in each state's online response to the pandemic. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.

Effective Communication Strategy to Mitigate Citizen Complaints: Case from Kazakhstan

This paper explores the potential impacts of effective communication strategies on handling with citizen complaints. Governments from all over the world recently learnt a number of important lessons as a result of poor public relations during the COVID-19 outbreak. Public confusion and misunderstanding may result from poor government communication, not just during the global coronavirus pandemic. The purpose of this paper is to highlight the benefits of the recently launched eOtinish services for citizen complaints, as well as their implementation process, benefits, and obstacles. This quick analysis of Kazakhstan's evolving eOtinish program review is meant to serve as a conceptual starting point for future studies on effective e-government adoption. This article provides government with recommendations for establishing effective citizen complaint strategies through effective communication channels for use with the public. By using the eOtinish as a case study we propose to understand technological change in the public sector, in particular, how technology influences administrative capacity, through a new concept of technological capacity. The results of this study suggest in order to seek new solution in managing people complaint government reach to conclusion that implementation of technological changes fundamentally alter how public organizations function and how services are delivered. © 2022,Innovation Journal. All Rights Reserved.

Assessment of risk factors for thrombosis in ICU patients with COVID-19

Introduction: According to scientific studies, a high incidence of thrombotic events is known in hospitalized patients with COVID-19. Less than 50% of pulmonary embolisms (PE) are associated with signs of deep vein thrombosis (DVT) of the lower extremities. Background: To identify significant risk factors for thrombosis thrombosis (DVT) in intensive care patients with COVID-19. Materials and methods: We conducted a prospective cross-sectional study that included 465 adult patients with laboratory-confirmed COVID-19 admitted to the intensive care unit. All patients underwent computer tomography of the chest organs, ultrasound angioscanning of lower extremities, body mass index was calculated, the presence of comorbotity diseases and indicators of volumetric blood saturation were considered. The level of D-dimer in blood plasma, coagulation parameters (fibrinogen, factor VIII) were taken from laboratory parameters in calculations. For subgroups with 5 or fewer people, the chi-square test and Fisher's exact test were used. For quantitative variables, analysis of variance (ANOVA) and the Pearson and Spearman correlation coefficient were used. For multiple variables, ordered logistic regression models were built, with likelihood ratio tests performed to compare the models. Results: A total of 465 patients were included in the study. Comorbidities were present in 435 of 465 patients (93.55%) had at least one comorbidity. The most common was arterial hypertension - 370 (79.57%), followed by chronic heart failure - 196 (42.15%), obesity - 161 (34.62%), diabetes mellitus - 144 (30.97%), chronic renal failure (CRF) -58 (12.47%) and oncological diseases -25 (5.38%). The average body mass index was 29.7 kg/m2. In patients with DVT and venostasis, the body mass index (BMI) was more than 30 kg/m2 than without DVT (32.57+or-10.92 kg/m2, and 30.24+or-6.85 kg/m2, versus 29.22+or-6.46 kg/m2, respectively). Ultrasound angioscanning (USAS) confirmed deep vein thrombosis in 60 patients (13.8%) and was associated with older age (71.12+or-13.98 versus 67.20+or-11.16, p < 0.006), venous stasis was detected in 56 patients (12%) no DVT was detected in the rest of the studied patients. In the majority of cases, DVT was detected in the tibial segment -26 (43.33%), in 18 (30%) patients it was diagnosed in the popliteal veins and in 14 (23.33%) cases in the femoral segment. Diabetes mellitus (p=0.041), obesity (p=0.01) and CRF (p=0.028) were also significant risk factors for DVT. Conclusions: Significant risk factors for deep vein thrombosis in intensive care patients with COVID-19 are high levels of D-dimer (>=2.33 g/ml) and comorbidities such as obesity, chronic kidney failure, and diabetes mellitus.

Analysis of epidemiological features of COVID-19 in Pavlodar region

Introduction: Coronavirus infection (COVID-19), first reported at the end of 2019, which has spilled over into a worldwide pandemic and has affected all aspects of our modern lives. The aim is to study and analyze the epidemiological features of COVID-19 in the Pavlodar region. Materials and methods: Study design is a descriptive retrospective study analysis. The data were obtained from official sources of the Republican Center for e-Health of the Ministry of Health of the Republic of Kazakhstan. The study includes patients from June 30, 2020 to October 31, 2021 who received outpatient and inpatient treatment for coronavirus infection in medical institutions of the Pavlodar region. Study materials - uploading reports from the Republican Center for e-Health of the Ministry of Health of the Republic of Kazakhstan. Results: This article presents epidemiological data on the incidence of coronavirus infection in the population of Pavlodar region. The number of detected cases of COVID-19 from June 30, 2020 to October 31, 2021 was 29,443. Distribution of patients by sex predominated women - 17,831 (60.56%), than men - 11,612 (39.44%). The majority of cases were in the age group from 61 to 70 years old, with a male to female ratio of 1:1.54. Statistical significance was found between duration of stay and type of inpatient care (p < 0.001, VS-MPR*=2.135 x 10+22). Conclusion: The study showed that the number of women who fell ill prevailed over the number of men who fell ill, although the number of deaths among men prevailed over the number of deaths among women. In the study, there was no significant difference in the duration of stay for men and women in home care, compared to patients under 24-hour observation.

NOTE FROM THE EDITOR: Presidential Tweets, the U.S.–U.K. Free Trade Agreement, Humanitarian Intervention, and China's Bilateral Relations

" Words Matter: Presidents Obama and Trump, Twitter, and U.S. Soft Power. Graph [9] concentrate on the issues that soured the initial optimism for a U.S.-U.K. free trade agreement between President Trump and Prime Minister Johnson which did not come to its planned fruition by 2020. EN Social Media Foreign Policy Twitter Soft Power Obama Trump Boris Johnson Humanitarian Intervention President Clinton Bosnia Kosovo China Sri-Lanka Kazakhstan South Korea ASEAN Sub-Saharan Africa Information Technology. NOTE FROM THE EDITOR: Presidential Tweets, the U.S.-U.K. Free Trade Agreement, Humanitarian Intervention, and China's Bilateral Relations. [Extracted from the article] Copyright of World Affairs is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)

Untangling the Integral Impact of Land Use Change, Economic, Ecological and Social Factors on the Development of Burabay District (Kazakhstan) during the Period 1999–2021

Long-term spatiotemporal Land Use and Land Cover (LULC) analysis is an objective tool for assessing patterns of sustainable development (SD). The basic purpose of this research is to define the Driving Mechanisms (DM) and assess the trend of SD in the Burabay district (Kazakhstan), which includes a city, an agro-industrial complex, and a national natural park, based on the integrated use of spatiotemporal data (STD), economic, environmental, and social (EES) indicators. The research was performed on the GEE platform using Landsat and Random Forest. The DM were studied by Multiple Linear Regression and Principal Component Analysis. SD trend was assessed through sequential transformations, aggregations, and integrations of 36 original STD and EES indicators. The overall classification accuracy was 0.85–0.97. Over the past 23 years, pasture area has changed the most (−16.69%), followed by arable land (+14.72%), forest area increased slightly (+1.81%), and built-up land—only +0.16%. The DM of development of the AOI are mainly economic components. There has been a noticeable drop in the development growth of the study area in 2021, which is apparently a consequence of the COVID-19. The upshots of the research can serve as a foundation for evaluating SD and LULC policy.

The Impact of the Pandemic on Educational Migration: Case Studies from India and China

The paper explores the impact of the coronavirus pandemic on educational migration. It emphasizes that the crisis has mostly affected education as well as all areas of the world community. The paper focuses on the situation of young people wishing to get an education abroad with the prospect of staying in the chosen country for permanent residence. Therefore, it is no coincidence that we have chosen such countries as China and India for the primary analysis, in which there are many young people in general and those who strive to get an education and gain permanent residence abroad in particular. The research issues are solved using dialectical, systemic, comparative, and statistical methods. In addition, we use the results of sociological research. This paper contributes to the development of a new urgent issue of the impact of the coronavirus pandemic on the world community, primarily on its educational area in young people migration. The paper is conceived within the scientific project framework by the Ministry of Education and Science of the Republic of Kazakhstan, "Educational Migration from Kazakhstan: Factors, Trends, and Social-Political Consequences.” © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.

Parkinson's Disease Awareness Among Medical Professionals In Kazakhstan

Objective: to assess the awareness of Parkinson's disease (PD) diagnosis and treatment among medical professionals in Kazakhstan. Background(s): PD is one of the most common neurodegenerative disease (1). Data on PD prevalence and incidence is lacking in Kazakhstan (2,3). Method(s): The original Thai questionnaire (4,5) was adapted, translated into the Russian language and validated. Questionnaire includes 20 questions divided into 3 groups: diagnosis of PD, treatment of PD and progression. The survey questionnaire was uploaded and shared online;printed forms were distributed to the medical staff in Almaty city. Result(s): 187 forms were collected, 20 printed forms were excluded after revising because of incorrect and incomplete filling (Fig.1): 48 male and 119 female responders. Mean age of responders was 36.34+/-10.933 years. 47.3% (79) of them work in the government hospitals, 50 (29.9%) are in the outpatient clinics, 33 (19.8%) are in the private clinics. The average experienced years after graduation are 12.16+/-11.696. Some of the responders has no practice with PD patients, but some of them accept 70 PD patients per month, average meaning is 5.23+/-9.562 patients per month. Average duration of residency of neurologists is 18.52+/-9.135 months. Only 14.4% of responders refer patients with PD to movement disorders specialist. Most popular medicines for PD treatment are Levodopa (70.06%), Pramipexol (25.75%), Amantadine (22.16%), only 9.58% of responders use DBS and less than 3% use pallidotomy and thalamotomy. 17.37% of responders has patients with foreign country treatment (43.8% other form of levodopa, 25% of levodopa +entocapone). 30.5% responders answered without mistakes, and only 9.6% mentioned all correct symptoms (Fig.2). 4.79% of responders mentioned all correct non-motor symptoms of PD (Fig.3). 74.3% of responders has supposed that neuroimaging is mandatory for diagnosing PD, 79.1% mentioned the rest tremor as obligatory symptom of PD (Fig.4). 81.4% of medical staff know that levodopa is the most effective medicine for PD patients. 50.9% of responders considered that SARSCov- 2 vaccine is contraindicated for PD patients (Fig.5). 83.8% of medical staff mentioned that PD medicines could slow down the progression of PD (Fig.6). Conclusion(s): Awareness of medical professionals in Kazakhstan about PD are poor. Educational programs are needed to improve quality and awareness of medical staff about PD.

How can distance learning offer opportunities for developing countries? Case of Turkey and Kazakhstan

Many scientific studies highlight emergency distance education's two fundamental problems during the COVID-19 pandemic. The first is the large number of students who need more access to communication technologies, and the second is the digital incompetence of educators and students. This study, which was prepared by Turkish and Kazakh academics working within the scope of the Bolashak scholarship program, aims to question the cooperation potentials for the development of distance education, which will become more critical in the future, and to propose policies to solve the main problems in the pandemic. In this context, the issues in Turkey and Kazakhstan during the pandemic were collected and generalised. SWOT analyses were conducted for the potential of cooperation between the two countries and both countries' exchange/internship programs. The findings show that both countries have intense distance education experiences, cooperation potential, and sufficient opportunities to strengthen weak elements by developing mobility and scholarship programs. Several strategies are suggested for these improvements. These recommendations provide a perspective for these two countries and all countries continuing distance education after the pandemic.

Study of the problems and prospects of small tourism business development in the city of Almaty

This study is based on an understanding of the state of development of small tourism businesses in Almaty, one of the oldest settlements located along the Great Silk Road. The aim of the study was to obtain accurate data on the current state of development of small tourism businesses in Almaty and to identify problems and prospects. In the course of the research, 655 questionnaire responses from business owners and managers meeting the selection criteria were selected and rigorously monitored over a period of 3 months. As a result of the study, the most important problems of small tourism businesses in Almaty were identified, which include: 75.7% of respondents lacked knowledge about tourism activities;53.6% of entrepreneurs do not conclude contracts with employees;82% of business representatives do not have marketing plans;and, as a consequence, inability to obtain loans from banks;and the consequences of the war in Ukraine. However, we also saw some positive trends in the survey: the willingness of respondents to overcome the consequences and the crisis of the covid pandemic-19;motivation to develop their own business;28.7% of young entrepreneurs;74.7% of individual entrepreneurs invest in small tourism businesses. Thus, this study is an auxiliary tool for solving the problem of sustainable development of tourism infrastructure of Almaty, service activities, problems arising in small tourism business.

Approaches to Occupational Mobility under the Conditions of the Current Economic Crisis

The objectives of economic development in the modern world demand new approaches in the study, analysis and research of social aspects, labour markets and local and regional economic development in the context of the new transformations, the multiple crises that humanity is going through today. For the labour market, the geographical approach opens up the lens of analysis, formulation of priorities and the development of new methodologies that will help us build new theories and policies of local and regional economic development, the development of a labour market through the prism of economic geography. This approach will allow us to analyse the migration processes of occupational mobility and to develop viable policies and measures to create new jobs and ensure sustainable, smart and inclusive economic growth.

A retrospective analysis of treatment of COVID-19 with favipiravir

One of the potential therapeutic agents for treating COVID-19 is favipiravir (FPV). This retrospective study compared the treatment of COVID-19 with (FVP group) or without (control group) favipiravir. Demographic characteristics and initial clinical indicators in the two groups were comparable. The level of oxygen saturation, respiratory rate, and prevalence of chest pain in the FVP group returned to normal significantly earlier (on the seventh day) compared to the control group (p < 0.05). Improvement of patients' condition in the FVP group occurred significantly earlier than in the control group (p < 0.001). In conclusion, FVP treatment's efficacy was higher than the control management strategy and established an individualized set of therapeutic agents. However, more detailed studies are needed to evaluate the efficacy of COVID-19 treatment with favipiravir fully.

SG-APSIC1054: Sputnik-V postvaccination immunologic responses in nasal mucosa: A prospective cohort study in Kazakhstan

Objectives: Sputnik-V (Gam-COVID-Vac) is a recombinant adenoviral (rAdv) vector-based, COVID-19 vaccine now used in >70 countries. Mucosal immunity is thought to be important for protection against COVID-19. We did a prospective cohort study to assess Sputnik-V–elicited mucosal SARS-CoV-2 antibody responses. Methods: We divided 82 COVID-19–free participants into prior COVID-19 and no prior COVID-19 groups and followed them at day 21 after Sputnik-V dose 1′ (rAd5) and dose 2′ (rAd26). Nasopharyngeal swabs and blood were collected to perform SARS-CoV-2 diagnostic and immunologic assays. SARS-CoV-2 spike-specific IgG and IgA ELISAs were performed on both nasal swabs and blood. SARS-CoV-2 real-time RT-PCR testing was performed to exclude infectious influencing. Results: Nasal S-IgG levels increased 25-fold after dose 1′ (P < .001) and remained high after dose 2 in all participants. Prior COVID-19 exposure was associated with both elevated baseline mucosal IgG and IgA and higher postvaccination IgG, but not IgA, boost. Nasal IgA levels increased 16.5-fold after dose 1′ (P < .001) and remained high after dose 2' in all participants. Compared to dose 1′, Sputnik-V dose 2′ did not further increase either mucosal IgG levels (P = .626) or IgA levels (P = .609). Conclusions: A single dose of Sputnik-V boosted mucosal SARS-CoV-2 immunity. The effects of Sputnik-V dose 2′ on mucosal immunity were minimal. These findings indicate (1) that intramuscularly administered adenoviral vaccines enhance SARS-CoV-2 immunity via both systemic and mucosal routes and (2) that cost-effectiveness and the efficacy of Sputnik-V vaccination could be improved by adjusting the current prime-booster regimen and extending the 21-day interval between the doses. Trial registration: Registered on ClinicalTrials.gov (no. NCT04871841).